The defender was shown a straight red card after a heavy touch left him jumping in to retrieve the ball back from Young Boys’ Christopher Martins Pereira.
As a result, Wan Bissaka stood on the midfielder’s ankle and was immediately sent off with ten minutes of the first half left.
The 23-year-old’s dismissal meant Ole Gunner Soljskear was forced to move things around and Jadon Sancho’s night was soon cut short as he was replaced by Diogo Dalot.
Manchester United fans have been reacting to Wan Bissaka’s red card on social media, with many extremely frustrated with the poor challenge.
After seeing out the first half, the Red Devils’ manager brought on Raphael Varane to replace Donny van de Beek who had been handed a rare start for Manchester United.
Ole Gunner Soljskaer brought the Frenchman off to ensure Young Boys wouldn’t make a comeback as the Premier League side look to take three points back to Manchester.
Many fans were disappointed that Wan-Bissaka’s dismissal meant van de Beek was forced to return to the bench once again, despite impressing in the first half.