The Red Devils come off the back of a disappointing 4-2 defeat at the hands of Leicester City last weekend after taking the lead with a goal from Mason Greenwood.
Meanwhile, Liverpool have enjoyed a brilliant start to their Premier League campaign and put on a superb performance in their 5-0 annihilation of Watford in their previous league fixture.
Jurgen Klopp’s side can leapfrog Manchester City if they are to take all three points at Old Trafford today, while Manchester United can move back into the top four if they snatch a win.
Here are how the previous five meetings played out between the two rivals...
Manchester United 2-4 Liverpool
13th May 2021
Manchester United last faced Liverpool towards the end of the 2020-21 season and were beaten 4-2.
Bruno Fernandes initially opened the scoring with an early goal inside ten minutes, however first half goals from Diogo Jota and Roberto Firmino handed the visitors the lead before the Brazilian doubled his goal tally shortly after half-time.
Mohamed Salah’s 90th minute goal rubbed salt into the wounds of the United players and Jurgen Klopp celebrated his first win at Old Trafford.
Ole Gunnar Solskjær’s side were left ten points behind their Manchester rivals and remained second in the league, while Liverpool increased their chances of Champions League football as they moved up to fifth - four points behind Chelsea.
Manchester United 3-2 Liverpool
24th January 2021
Manchester United hosted Liverpool in the fourth round of the FA Cup at the start of the year and came out 3-2 winners.
Mohamed Salah picked up a brace away from home, however it wasn’t enough to stop their rivals from progressing to the next round, with Mason Greenwood, Marcus Rashford and Bruno Fernandes scoring for the Red Devils.
United reached the quarter-finals of the FA Cup but were knocked out by Leicester City.
Liverpool 0-0 Manchester United
17th January 2021
Liverpool were held to a draw by Manchester United in a 0-0 stalemate only a week prior to their FA Cup clash.
The Reds were going through a tough patch and were without a win in four consecutive games in the Premier League and had also failed to score in three successive matches in the league for the first time since March 2005.
Meanwhile, the Red Devils remained top of the table after their first goalless away draw since their visit to West Ham in May 2018.
Liverpool 2-0 Manchester United
19 January 2020
Their previous meeting came a year previous to the 0-0 draw but this time Liverpool came out victorious.
Virgil Van Dijk bagged an early goal before Salah doubled their lead right at the death, securing their position at the top of the table even further, while the visitors sat in fifth position - five points from the top four.
Liverpool’s win wasn’t much of a surprise given their superb form that season where they later won their first Premier League title.
Manchester United 1-1 Liverpool
20th October 2019
Manchester United were very disappointed to not walk away from this fixture with all three points after Adam Lallana snatched a draw for the visitors with a late equaliser.
Axel Tuanzebe was originally set to start for the home side, however he was replaced by Marcos Rojo following an injury in the warm-up - the Argentinian was later at fault for Lallana’s goal.
Despite the fact a draw would have felt like a loss at Old Trafford, the Red Devils had managed to put a stop to Liverpool’s flawless start to the Premier League season with Jurgen Klopp’s side sat top of the table.