Just five days will have passed since Steven Gerrard’s men suffered a narrow defeat at Old Trafford as an early Scott McTominay goal helped the Red Devils edge a tight FA Cup third round tie.
Villa impressed at the home of the 13-time Premier League champions and only an inspired display from Red Devils keeper David de Gea prevented them from forcing the tie into extra-time.
Debuts for Villa’s new signings?
Saturday’s Villa Park clash has been given an extra air of intrigue after Gerrard got his January transfer business underway with two impressive additions this week.
The Liverpool legend was reunited with his former Anfield team-mate Philippe Coutinho as the Brazilian playmaker officially completed a loan move from Barcelona on Monday.
A second piece of business quickly followed on Thursday when Villa secured a reported £25m move for Everton left-back Lucas Digne.
Both players could be handed immediate starts as their new side go looking for a win that could take them towards the top half of the Premier League table.
Ronaldo to return for the visitors?
Following an underwhelming spell of form in the Premier League, the Red Devils will arrive at Villa Park desperately looking for a win that would keep them in contention for a Champions League spot.
Following last week’s home defeat against Wolves, Ralf Rangnick’s side currently sit six points adrift of West Ham United, who currently occupy the fourth and final Champions League spot.
The German coach will hope the return of Portuguese legend Cristiano Ronaldo can inspire his side to a fourth consecutive win at Villa Park.
Where to watch the game live
The game kicks off at 5.30pm on Saturday and will be broadcast live on Sky Sports Main Event and Sky Sports Premier League.
Coverage gets underway at 5pm.