England kick off their 2022 World Cup qualifying campaign at home to San Marino - in the first of three key Group I fixtures in six days.
Gareth Southgate’s Three Lions will also face Albania and Poland during the international match week in what they hope will be their first steps on the road to Qatar qualification.
England have won all six matches played against San Marino, have never scored less than five goals in each fixture and have conceded just once - in a 7-1 win back in 1993.
San Marino are the worst FIFA ranked national team in the world, with bookies saying there is more chance of the UK winning the Eurovision song contest than a Wembley upset tonight.
When is England v San Marino?
England begin their 2022 World Cup qualifying campaign against San Marino on Thursday 25 March 2021.
The fixture will be the first meeting between the two nations since 2015 when England ran out 6-0 winners over San Marino in a Euros qualifier.
Wayne Rooney, Ross Barkley, Theo Walcott and Harry Kane were on target that day away to San Marino, who were beaten 5-0 in the reverse fixture.
What time does England v San Marino kick off?
England v San Marino kicks off at 7.45pm on 25 March.
Where is England v San Marino being played?
Wembley Stadium will host England vs San Marino.
What TV channel is England v San Marino on?
England’s World Cup qualifier against San Marino will be televised live from Wembley on ITV.
What time does TV coverage of England v San Marino start?
TV coverage of England v San Marino begins at 7.15pm - 30 minutes before kick off - and will run through to 10pm.
How can I live stream England v San Marino?
The match between England and San Marino will be televised but can also be streamed through the ITV Hub app on smart TVs, digital devices, computers and smartphones.
What are the latest odds on England v San Marino?
Unsurprisingly, England are the overwhelming favourites to beat San Marino at Wembley with the online bookies giving odds of 1/100 to 1/200 on a home win.
San Marino aren’t thought to hold much hope of registering an unlikely win against England, with SpreadEx giving odds of 750/1 - by far the best offering for a punt.
Other odds include 100/1 with Bet365, UniBet, BetWay and BoyleSports; 200/1 with PaddyPower; 250/1 with BetFair and 499/1 with SBK according to oddschecker.com.
Odds of a draw are at 50/1 with Bet365 and PaddyPower, and 199/1 with SBK who aren’t taking bets on an England victory to kick off the World Cup qualifying campaign.
Who is in the England squad?
Goalkeepers: Dean Henderson (Manchester United), Sam Johnstone (West Bromwich Albion), Nick Pope (Burnley).
Defenders: Ben Chilwell (Chelsea), Conor Coady (Wolverhampton Wanderers), Eric Dier (Tottenham Hotspur), Reece James (Chelsea), Harry Maguire (Manchester United), Tyrone Mings (Aston Villa), Luke Shaw (Manchester United), John Stones (Manchester City), Kieran Trippier (Atletico Madrid), Kyle Walker (Manchester City).
Midfielders: Jude Bellingham (Borussia Dortmund), Phil Foden (Manchester City), Jesse Lingard (West Ham United, loan from Manchester United), Mason Mount (Chelsea), Kalvin Phillips (Leeds United), Declan Rice (West Ham United), James Ward-Prowse (Southampton).
Forwards: Dominic Calvert-Lewin (Everton), Harry Kane (Tottenham Hotspur), Marcus Rashford (Manchester United), Bukayo Saka (Arsenal), Raheem Sterling (Manchester City), Ollie Watkins (Aston Villa).
How England could line up:
England (3-5-2): Henderson, Walker, Maguire, Stones, Dier, Rice, Mount, Lingard, Foden, Kane, Watkins