Dopamine: reaction time is improved following a bout of exercise, scientists say

Dopamine is a key cause of improved reaction times following exercise, as scientists found the reaction time of cyclists improved as dopamine levels increased.

Scientists at the University of Portsmouth say the findings could lead to new exercise-based treatments to improve cognitive health for conditions including Parkinson’s disease, schizophrenia, ADHD, addiction and depression.

Dr Joe Costello, from the university’s school of sport, health and exercise science, said: “We know cardiovascular exercise improves cognitive performance, but the exact mechanisms behind this process have not been rigorously investigated in humans until now. Using novel brain-imaging techniques, we were able to examine the role dopamine plays in boosting brain function during exercise, and the results are really promising.

“Our current study suggests the hormone is an important neuromodulator for improved reaction time. These findings support growing evidence that exercise prescription is a viable therapy for a host of health conditions across the lifespan.”

For the study, published in the Journal of Physiology, 52 male participants were asked to carry out cognitive tasks at rest and while cycling in a positron emission tomography (PET) scanner which monitored the movement of dopamine in their brain.

The results suggested that when a participant cycled lying down in the machine, their brain increased the amount of dopamine release and that this process was linked with improved reaction time.

A second experiment used electrical muscle stimulation to test whether forced muscle movement to stimulate exercise would also improve cognitive performance and a final experiment combined both voluntary and involuntary exercise. In the experiments where voluntary exercise was carried out, cognitive performance improved but the researchers found this was not the case when only forced electrical stimulation was used.

Sochi Ando, associate professor in the health and sports science laboratory at the University of Electro-Communications in Japan, said: “This suggests that when we tell our central command to move our body during a workout, that’s the process which helps the dopamine release in the brain.”

Dr Costello added: “These latest findings support our previous theory that cognitive performance during exercise is affected by changes to brain-regulating hormones, including dopamine. There could also be a number of other psychophysiological factors including cerebral blood flow, arousal and motivation that play a part.”